WHAT IS IT?
LGD-4033 is a selective androgen receptor modulator (SARM) developed to be a potential treatment for a variety of musculoskeletal degenerative diseases. The main goal of all SARMs essentially boils down to finding the right compound that provides the same therapeutic benefits of testosterone with improved safety, tolerability and patient acceptance. So far, LGD-4033 has demonstrated an incredible profile, and the clinical data suggests it could be a best-in-class small molecule SARM.
WHAT ARE THE RESULTS?
Gains upwards of 5-10 pounds of lean muscle mass are commonly reported among recreational users within a 4-8-week cycle. LGD-4033 is often referred to as the best mass building SARM, as it seems to exhibit greater muscle building potential than all other first-generation SARMs. Typically, it is incorporated into bulking phases where LIGANDROL is used to enhance strength and hypertrophy while concurrently being in a caloric surplus. Substantial increases in strength are commonplace among recreational users as well. A handful of users have reported increases in strength of their flat barbell bench press, squat, and/or deadlift by as much as 100 pounds in a focused bulking phase. If a diet comprised of enough macronutrients, micronutrients and overall calories is adhered to for the duration of an LGD-4033 cycle, anecdotal reports suggest that gains of muscle upwards of 10 pounds and strength gains of 50-100 pounds on compound exercises are realistic.
While LGD-4033 was generally regarded as safe in human trials using dosages as high as 22 mg per day, that doesn’t mean it had no negative side effects. The clinical data shows dose-dependent suppression of HDL cholesterol and triglyceride levels with LGD-4033 usage.
SARMs have shown to suppress luteinizing hormone (LH) and follicle stimulating hormone (FSH) through the hypothalamus-pituitary-testis axis, thus decreasing testosterone in a dose-dependent manner. LGD-4033 significantly lowered Sex Hormone-Binding Globulin (SHBG) and total testosterone in clinical trials, resulting in a reduction of serum free testosterone in subjects treated with 1 mg of LGD-4033. The degree to which even high dosages of LGD-4033 suppress LH and FSH is far less than that of traditional anabolic steroids.
LIGANDROL does not aromatize into Estrogen, however, by suppressing natural Testosterone levels it can create an unfavorable balance between Testosterone and Estrogen in the body. By occupying the androgen receptor with such a high affinity, the supplement can divert a significant amount of Testosterone to aromatize into Estrogen that wouldn’t have otherwise. The consequence of this is a systemic elevation of Estrogen levels in the body, which is commonly misinterpreted as prohormone laced SARMs.
ON CYCLE SUPPORT AND POST CYCLE THERAPY ARE NEEDED!