SOLARAY BERBERINE

$16.99

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Description

Berberine: Still a Staple 3000+ Years Later

Used traditionally for more than 3,000 years, Berberine is a golden yellow alkaloid extracted from the roots and stems of plants such as Indian Barberry.

From gut health support to immune function and beyond, Berberine is a staple you’ll want to add to your supplement cabinet if you haven’t already!

 

Why Berberine?

A golden yellow alkaloid, Berberine HCl is extracted from the roots and stems of plants such as Indian Barberry. Traditionally used for more than 3,000 years, Berberine may help support:

  • Healthy Digestion
  • Gut Health
  • Immune Function
  • Healthy Blood Sugar Balance
  • Metabolism Regulation

AMPK Activator

Berberine is also an AMPK Activator. Those following the ketogenic diet appreciate the reputed role Berberine plays as a metabolic regulator that supports the body’s:

  • Metabolization of fatty acids
  • Production of cholesterol/triglycerides
  • Usage and storage of glucose
  • Making ketones.

Why Solaray?

In 1973, Solaray began to formulate herbal blends for specific health benefits. Over the years, Solaray pioneered many innovative remedies and became a trusted full-line dietary supplement brand found in health food stores all around the world. True to our commitment to stay leading edge in powerful supplementation, we are proud to offer our Berberine 500 mg! Our quality is a difference that you can feel.

Feel the difference with Solaray Berberine 500!

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Uses & Effectiveness?

Possibly Effective for

  • Canker sores. Research shows that applying a gel containing berberine can reduce pain, redness, oozing, and the size of ulcers in people with canker sores.
  • Diabetes. Berberine seems to slightly reduce blood sugar levels in people with diabetes. Also, some early research shows that taking 500 mg of berberine 2-3 times daily for up to 3 months might control blood sugar as effectively as metformin or rosiglitazone.
  • High levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia). Berberine might help lower cholesterol levels in people with high cholesterol. Taking berberine for up to 2 years seems to reduce total cholesterol, low-density lipoprotein (LDL or “bad”) cholesterol, and triglyceride levels in people with high cholesterol. When compared with standard cholesterol-lowering medications, berberine appears to cause similar changes in total cholesterol, LDL cholesterol, and high-density lipoprotein (HDL or “good”) cholesterol, and it might be better at reducing triglyceride levels.
  • High blood pressure. Taking 0.9 grams of berberine per day along with the blood pressure-lowering drug amlodipine reduces systolic blood pressure (the top number) and diastolic blood pressure (the bottom number) better than taking amlodipine alone in people with high blood pressure.
  • A hormonal disorder that causes enlarged ovaries with cysts (polycystic ovary syndrome or PCOS). Research shows that berberine can lower blood sugar, improve cholesterol and triglyceride levels, reduce testosterone levels, and lower waist-to-hip ratio in women with PCOS. Berberine may even lower blood sugar levels similar to metformin and may improve cholesterol levels better than metformin. It is unclear if berberine increases pregnancy rates or live birth rates in women with PCOS.

Insufficient Evidence for

  • Burns. Early research shows that applying an ointment that contains berberine and beta-sitosterol can treat second-degree burns as effectively as conventional treatment with silver sulfadiazine.
  • An infection of the intestines that causes diarrhea (cholera). Some early research shows that taking berberine sulfate can decrease diarrhea by a small amount in people with cholera. However, berberine does not seem to improve the effects of the antibiotic tetracycline in treating diarrhea related to cholera infection.
  • Non-cancerous growths in the large intestine and rectum (colorectal adenoma). Early research shows that taking berberine for 2 years seems to prevent regrowth of colorectal adenomas in people who have already been treated for these growths.
  • Heart failure and fluid build up in the body (congestive heart failure or CHF). Early research shows that berberine can reduce some of the symptoms and lower the death rate in some people with congestive heart failure.
  • Heart disease. Research shows that taking a specific product containing berberine and other ingredients for 3 months lowers cholesterol levels in people with heart disease who had a procedure called a percutaneous intervention (PCI). This product seems to lower cholesterol levels more than the standard medication ezetimibe, which is used to lower cholesterol. Also taking this product in combination with low doses of medicines called “statins” seems to work better than taking low-dose statins alone. It’s unclear if the effects of this product are due to berberine, other ingredients, or the combination. It’s also unknown whether this product reduces the risk of major adverse heart-related events in people with heart disease.
  • Diarrhea. Some early research shows that taking berberine sulfate can decrease diarrhea in people with an E. coli infection.
  • A group of eye disorders that can lead to vision loss (glaucoma). Early research shows that using eye drops containing berberine and tetrahydrozoline for does not reduce eye pressure in people with glaucoma better than eye drops containing tetrahydrozoline alone.
  • A digestive tract infection that can lead to ulcers (Helicobacter pylori or H. pylori). Early research shows that taking berberine is more effective than the drug ranitidine at treating H. pylori infection. But berberine seems less effective at healing ulcers in people with stomach ulcers due to H. pylori. Other research shows that berberine might treat H. pylori infection as well as the medication bismuth when taken in combination with a standard three-drug regimen for H. pylori infection.
  • Swelling (inflammation) of the liver caused by the hepatitis B virus (hepatitis B). Early research shows that berberine decreases blood sugar, blood fats called triglycerides, and markers of liver damage in people with diabetes and hepatitis B.
  • Swelling (inflammation) of the liver caused by the hepatitis C virus (hepatitis C). Early research shows that berberine decreases blood sugar, blood fats called triglycerides, and markers of liver damage in people with diabetes and hepatitis C.
  • A long-term disorder of the large intestines that causes stomach pain (irritable bowel syndrome or IBS). Early research shows taking that berberine twice daily for 8 weeks might reduce diarrhea and stomach pain and might improve quality of life in people with IBS with diarrhea.
  • Symptoms of menopause. Early research shows that taking a combination of berberine and soy isoflavones can reduce menopausal symptoms. However, it’s not clear if berberine reduces menopausal symptoms if used alone.
  • A grouping of symptoms that increase the risk of diabetes, heart disease, and stroke (metabolic syndrome). Early research shows that berberine reduces body mass index (BMI), systolic blood pressure (the top number), blood fats called triglycerides, and blood sugar levels in people with metabolic syndrome. It also seems to improve insulin sensitivity. Other early research suggests that taking a combination product containing berberine, policosanol, red yeast rice, folic acid, coenzyme Q10, and astaxanthin improves blood pressure and blood flow in people with metabolic syndrome.
  • Build up of fat in the liver in people who drink little or no alcohol (nonalcoholic fatty liver disease or NAFLD). Early research shows that berberine reduces fat in the blood and markers of liver injury in people with diabetes and liver disease not caused by alcohol. Other early research shows that berberine might reduce fat on the liver, markers of liver injury, and weight in people with this condition. Berberine seems to work about as well as the medication pioglitazone.
  • Obesity. Early research shows that taking berberine can reduce weight in obese people by about 5 pounds.
  • Weak and brittle bones (osteoporosis). Early research shows that taking berberine together with vitamin D3, vitamin K, and a chemical found in hops can decrease bone loss in postmenopausal women with osteoporosis. Its not known if berberine is beneficial if taken by itself.
  • Diarrhea caused by radiation therapy. Some early research shows that taking berberine during radiation therapy can reduce intestinal injury from radiation in patients being treated for cancer.
  • Scarring of tissue caused by radiation therapy. Some early research shows that taking berberine during radiation therapy can reduce lung injury from radiation in patients being treated for cancer.
  • Low levels of platelets in the blood (thrombocytopenia). Blood platelets are important for blood clotting. Early research shows that taking berberine either alone or with prednisolone, can increase the number of blood platelets in people with low blood platelet counts.
  • An eye infection caused by Chlamydia trachomatis (trachoma). There is some evidence that eye drops containing berberine might be useful for treating trachoma, a common cause of blindness in developing countries.
  • A type of inflammatory bowel disease (ulcerative colitis). Early research shows that taking berberine does not seem to improve symptoms in people with ulcerative colitis who take the drug mesalamine.
  • Other conditions.

More evidence is needed to rate the effectiveness of berberine for these uses.

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  • Zhang D, Ke L, Ni Z, Chen Y, Zhang LH, Zhu SH, et al. Berberine containing quadruple therapy for initial Helicobacter pylori eradication: An open-label randomized phase IV trial. Medicine (Baltimore). 2017;96(32):e7697. doi: 10.1097/MD.0000000000007697. View abstract.
  • Zhang LS, Zhang JH, Feng R, et al. Efficacy and safety of berberine alone or combined with statins for the treatment of hyperlipidemia: a systematic review and meta-analysis of randomized controlled clinical trials. Am J Chin Med 2019;47(4):751-67. View abstract.
  • Zhang Y, Li X, Zou D, et al. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. J Clin Endocrinol Metab 2008;93:2559-65. View abstract.

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